On May 24, 2016 , the USPTO issued U.S. Patent Number 9,345,879 to EndoStim, Inc. , which was successfully prosecuted by Novel IP.
The '879 patent is directed towards devices and methodologies for the treatment of transient lower esophageal sphincter relaxations (tLESRs). Individuals with tLESRs may be treated by implanting a stimulation device within the patient's lower esophageal sphincter and applying electrical stimulation to the patient's lower esophageal sphincter, in accordance with certain predefined protocols. The presently disclosed devices have a simplified design because they do not require sensing systems capable of sensing when a person is engaged in a wet swallow and have improved energy storage requirements.
Independent Claim 1 describes " A system for treating a gastrointestinal condition of a patient, comprising: a pulse generator in electrical communication with at least one electrode, wherein said pulse generator is adapted to be implanted such that said electrode is configured to be in electrical communication with a lower esophageal sphincter (LES) of the patient, and wherein said pulse generator generates a pulse stream in accordance with a preset period; an energy storage component; and a non-volatile memory for storing programmatic code which, when executed by a processor, causes said pulse generator to generate the pulse stream for the preset period, wherein said pulse stream comprises a pulse width having a range of 30 μsec to 5 msec, a pulse amplitude having a range of 2 to 15 mAmp, a pulse frequency having a range of 2 to 80 Hz, an on period having a range of 1 second to 23 hours, 59 minutes, and 59 seconds, an off period having a range of 1 second to 23 hours, 59 minutes, and 59 seconds, and a duty cycle having a range of 1 to 100%, wherein values for each of said pulse width, pulse amplitude, and pulse frequency are defined such that swallowing of the patient is not hindered by said stimulation while said stimulation is occurring. "